High-grade gliomas

Glioblastoma multiforme and anaplastic astrocytomas are high-grade brain tumors, meaning they grow quickly and can spread into nearby brain tissue. Our specialists guide patients from diagnosis through treatment with expertise and support.

Types of high-grade gliomas

These high-grade gliomas originate from the supportive tissue of the brain (glial cells). There are several types of these tumors, including astrocytomas. These tumors are classified into four grades that reflect their degree of severity. The highest grade is the most malignant (cancerous) and fast-growing. They can arise at any age, but are more common in adult patients.

Astrocytomas - a form of glioma named after astrocytes, the star-shaped glial cells which support and regulate electrical impulses in the brain. They are widely distributed throughout the brain and spinal cord. Anaplastic astrocytomas are high-grade (grades III and IV), malignant gliomas that are some of the most common primary brain tumors in adults. 

Glioblastoma multiforme (GBM) -  the most aggressive type of astrocytoma and highest-grade (grade IV) glioma. The most common primary brain tumor in adults, they usually arise sporadically but can also develop from lower grade gliomas. These tumors are invasive and commonly spread throughout the brain.


Brain tumor clinical trials

We offer patients hope through a robust clinical trial research program to discover the next generation of brain tumor treatments.

Brain tumor research.

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